Medicinal Chemistry in Drug Development

Medicinal Chemistry in Drug Development offers a detailed exploration of the chemical principles that are crucial in the discovery and development of pharmaceutical agents. The book is structured to guide readers from basic concepts to advanced applications in a progressive manner. It begins with an overview of drug targets and molecular interactions, and then delves into drug discovery processes, lead identification, and optimization strategies. A special focus is given to understanding how the structure of a molecule influences its biological activity and pharmacological properties. Topics such as ADME (Absorption, Distribution, Metabolism, and Excretion), toxicology, stereochemistry, and computational drug design are thoroughly covered.
Real-life examples from successful drug development programs are included to provide context and relevance. This book is ideal for students of pharmacy, pharmaceutical chemistry, and life sciences, as well as researchers and professionals involved in drug discovery and development. By combining theoretical frameworks with practical insights, it equips readers with the scientific knowledge necessary to contribute meaningfully to the pharmaceutical field. The goal is to foster a deeper appreciation of how medicinal chemistry serves as a critical pillar in the journey from molecule to medicine.